Chromosomal Microarray Analysis (Cytogenetics) – both Both Baylor and Centogene use CMA and not cyto.
Chromosomal microarray analysis (CMA) is a molecular cytogenetic method for analyzing copy number variations.
Our microarray-based solution enables detection of known and novel structural aberrations, such as copy number variations (CNVs), chromosomal imbalances, regions exhibiting loss/absence of heterozygosity (LOH), uniparental isodisomy (UPD), and mosaicism.
CMA is a diagnostic test recommended by the American Academy of Neurology (AAN), the American College of Medical Genetics (ACMG), the Child Neurology Society (CNS), the American Academy of Pediatrics (AAP), and the International Standard Cytogenomic Array (ISCA) Consortium.
Why do the test?
Through its ability to detect structural aberrations, Cytogenetics can provide information on thousands of targets in a single experiment that can detect copy number changes at the gene, chromosome, and genome level. Chromosomal microarray analysis is recommended as a first-step analysis for individuals with signs of intellectual disability, developmental delay, autism spectrum disorder, or multiple congenital anomalies, as it provides comprehensive genetic testing for the most common chromosomal conditions as well as a large number of severe genetic conditions not detected by traditional chromosome analysis. Additionally, it enables the detection of copy number variations and/or large deletions/duplications.
Prenatal CMA compares specific regions of an unborn child’s DNA to that of a normal genome, which may provide vital information to help manage your patient’s pregnancy. Using NoorDX to test for this may help to determine the cause of ultrasound-detected abnormalities.
Through its ability to detect structural aberrations, Cytogenetics can provide information on thousands of targets in a single experiment that can detect copy number changes at the gene, chromosome, and genome level.
• Chromosomal microarray analysis is recommended as a first-step analysis for individuals with signs of intellectual disability, developmental delay, autism spectrum disorder, or multiple congenital anomalies, as it provides comprehensive genetic testing for the most common chromosomal conditions as well as a large number of severe genetic conditions not detected by traditional chromosome analysis. Additionally, it enables the detection of copy number variations and/or large deletions/duplications.
• Prenatal CMA compares specific regions of an unborn child’s DNA to that of a normal genome, which may provide vital information to help manage your patient’s pregnancy. The test may help to determine the cause of ultrasound-detected abnormalities.
Why choose NoorDx?
Rapid
Delivering results in days
Innovative
Pioneering solutions in genomics testing to save lives
Confidential
Providing the highest levels of patient privacy and advanced data security
World-class
Granting access to a team of expert genetics within our state-of-the-art lab